NEWS and OPINIONS

Researchers Find Treatment Options for Patients Whose Blood Cancer Relapses After CAR-T
Addresses major gap in effectiveness of immunotherapy Mount Sinai Press Release New York, NY - Mount Sinai and Memorial Sloan Kettering Cancer Center (MSK) researchers have identified therapies that can help patients with the blood cancer multiple myeloma who try an...

UC San Diego School of Medicine Finds STEM Cell Rehabilitation Treatment for Spinal Cord Injuries
By University of California - The Guardian UC San Diego School of Medicine’s Translational Neuroscience Institute made its latest breakthrough in the treatment of spinal cord injuries after the culmination of 30 years of research. In a paper published on Aug. 22, a...

Mayo Clinic Researchers ID Potential Gene Marker for Treating Pancreatic Cancer
By Joe Dangor - Mayo Clinic ROCHESTER, Minn. — Researchers at Mayo Clinic Comprehensive Cancer Center have identified a gene marker that may lead to a more effective, precision treatment for pancreatic ductal adenocarcinoma (PDAC). The researcher’s findings are...

CRISPR cancer trial success paves the way for personalized treatments
By Heidi Ledford - Nature ‘Most complicated therapy ever’ tailors bespoke, genome-edited immune cells to attack tumours. A small clinical trial has shown that researchers can use CRISPR gene editing to alter immune cells so that they will recognize mutated proteins...

Addressing the challenges of chimeric antigen receptor-T cell therapy
By Susan Murphy - Mayo Clinic Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) — a type of immunotherapy that reprograms a patient's T cells to recognize and destroy cancer cells — has revolutionized the treatment of blood cancers. While the technique has...

Monoclonal antibodies preserve stem cells in mouse brains, bring promise for future studies
By Noah Fromson - University of Michigan Health Image caption: Human neural stem cell transplants (green) survive and migrate throughout the mouse brain (blue) when given a novel monoclonal antibody treatment. Michigan Medicine Using antibodies instead of traditional...

Cell and Gene Therapy: Current Challenges and the Benefits of Automation
By Anna MacDonald and Sarah Whelan - Technology Networks Cell and gene therapy is a field of personalized medicine, driving the innovation of medicine and revolutionizing the way we treat disease. Gene therapies use DNA or other genetic material to edit a patient's...

Trial of Stem Cell-derived Therapy for Parkinson’s to Open in Sweden
by Margarida Maia, PhD - Parkinson's News Today A request to launch a first Phase 1/2 clinical trial of a stem cell-based therapy in people with Parkinson’s disease has been approved by the Swedish Medical Products Agency. The therapy, called STEM-PD, consists of stem...

A stress test for blood stem cells
by Nature Italy By studying how hematopoietic stem cells respond to age and damage, Raffaella di Micco aims to anticipate the long-term effects of some gene therapies. This is a scene from my daily routine in my lab in Milan where we study hematopoietic stem cells,...

Ground-breaking stem cell procedure restores patient’s mobility and joy for life
By The Ottawa Hospital - The Globe and Mail Treatment developed at The Ottawa Hospital can halt MS progression and potentially reverse symptoms When Geneviève Bétournay developed blurry vision and pain in her hips 12 years ago, she was shocked to be diagnosed with...

Researchers use CRISPR-edited T cells to treat seriously ill children with resistant leukaemia
By Medical News Life Sciences Researchers at Great Ormond Street Hospital for Children (GOSH) and UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) have used CRISPR/Cas9 technology to engineer donor T cells to try to treat seriously ill children with...

Stem Cell Study Shows How Neurons from PTSD Patients React to Stress
By Genetic Engineering & Biotechnology News A study by scientists at the Icahn School of Medicine at Mount Sinai, the James J. Peters Veterans Affairs Medical Center, the Yale School of Medicine, and the New York Stem Cell Foundation Research Institute (NYSCF) has...