NEWS and OPINIONS
CRISPR Gets an Invisibility Cloak
By Technology Networks - Scientists created an immunity-proof CRISPR system that reveals hidden metastasis genes in mouse tumour models. The immune system plays a crucial role in fighting tumours and metastases. Consequently, it is decisive to conduct cancer research...
The vital, overlooked role of body fat in shaping your health and mind
By Linda Geddes - NewScientist - f you melted down the average UK adult, you’d find around 22 kilograms (48.5 pounds) of creamy yellow fat – equivalent to around 88 blocks of lard, enough to fill two-thirds of a small suitcase or cast into 446 dinner candles. Melted,...
Crispr gene-editing technology offers new hope for HIV cure but faces delivery challenges
By Tosin Thompson - Chemistry World - Two years ago, the UK became the first country to approve Casgevy, a Crispr-based therapy for the blood disorders sickle cell disease and β-thalassaemia. This year saw the world’s first personalised Crispr therapy for a baby boy...
Vycellix Prepares for First-in-Human Study of Novel Allogeneic Cell Therapy Powered by Its Universal Cell Engineering Platform
By Vycellix - - Single-step CD45-engager technology shows robust immune evasion with functional persistence in pre-clinical models - Phase 1 study to evaluate ‘off-the-shelf’ natural killer cell cancer immunotherapy in the treatment of multiple myeloma BOCA RATON,...
Scientists use stem cells to model rare genetic blindness in children
by Children's Medical Research Institute - MedicalXpress - Researchers at the Eye Genetics Research Unit at Children's Medical Research Institute (CMRI) are the first in the world to use stem cells to study one of the genetic causes of Leber Congenital Amaurosis...
New nanotech method loads stem cells with extra mitochondria to recharge dying cells
by Aamir Khollam - Interesting Engineering - Texas A&M scientists used nanoflower-boosted stem cells to deliver extra mitochondria to weakened cells, restoring lost energy and improving survival under stress. Scientists at Texas A&M University say they may have found...
The resurgence of mesenchymal stem cell therapies
By Miranda McLaren - Clinical Trials Alerts - Mesenchymal stem cells have been explored across a wide range of diseases due to their potential to reduce inflammation and promote tissue repair and regeneration. BBG Advanced Therapies’ Rogelio Zamilpa, PhD takes us...
Artificial intelligence and systems biology analysis in stem cell research and therapeutics development
By Stem Cells Translational Medicine - Background: Stem cell research has rapidly advanced during the past decades, but the translation into approved clinical products is still lagging behind. Multiple barriers to effective clinical translation exist. We hypothesize...
Inflammation turns bone marrow into a breeding ground for disease
By Science Daily - Inflammation covertly rewires the bone marrow, enabling mutated stem cells to rise and setting the stage for future blood disease. Researchers discovered that chronic inflammation fundamentally remodels the bone marrow, allowing mutated stem cell...
Bone Marrow Model Created Entirely from Human Cells
By Genetic Engineering and Biotechnology News - Typically, bone marrow research relies heavily on animal models and oversimplified cell cultures in the laboratory. Now, researchers from the Department of Biomedicine at the University of Basel and University Hospital...
Scientists see foam as starting point of a path to bedside gene therapy
By Sabrina Richards - Fred Hutch Cancer Center - Bioengineer Dr. Matthias Stephan developed a quick-foaming solution that he hopes could one day turn gene therapy into an outpatient procedure The special properties of methylcellulose foam could make it a vehicle for...
Japanese Researchers Develop Method to Repair Spinal Fractures Using Fat-Derived Stem Cells
by GOAI -Gene Online - Japanese researchers are exploring a novel, minimally invasive method to repair spinal fractures using body fat-derived cells. The experimental approach involves converting fat cells into bone tissue, offering a potential alternative to...