BY Carrie MacMillan – Yale Medicine –

CAR-T cell therapy, approved to treat some blood cancers, is now being studied for lupus, multiple sclerosis, and scleroderma. Yale Medicine experts explain how it works, its risks, and who can benefit.

It may sound like science fiction: removing a person’s immune cells, modifying them in a lab, and putting them back into the body to target the cells causing disease. But medical experts believe the approach, known as chimeric antigen receptor T-cell (CAR-T) therapy, could someday help treat a growing list of hard-to-manage conditions.

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