NEWS and OPINIONS
A CRISPR Tool for Tinkering with the Human Transcriptome
By Danielle Gerhard, PhD - The Scientist - ike the find-and-replace feature of a word processor, CRISPR-based engineering allows scientists to quickly and efficiently edit DNA sequences with base pair precision. Lauded as the great democratizer of gene editing, CRISPR...
Paving the way for future larynx transplants through regenerative science
By Susan Buckles - Mayo Clinic - Mayo Clinic envisions a day when regenerative science makes it possible to offer a total larynx transplant to anyone who needs one. The research team of David Lott, M.D., hopes to overcome a shortage of donor organs and minimize the...
Scientists develop first bone marrow model that supports human stem cells
By University of Glasgow - MedicalXpress - Scientists have created the first bioengineered bone marrow model that can support the type of human stem cells that are crucial for bone marrow transplants and in vitro study work. The research—published in Nature...
Safe Pregnancies Possible After Stem Cell Treatment for Blood Cancer
By Ernie Mundell - USNews - Women who've undergone stem cell treatments for blood cancers, or for illnesses such as sickle cell disease, can successfully bring a pregnancy to term, new research shows. The German findings run counter to the perceived wisdom on this...
Stem Cell Therapies Considered Interchangeable Contain Different Cell Types
By Genetic Engineering & Biotechnology News - Researchers at the University of California San Diego (UCSD) have found that two of the most frequently administered stem cell therapies, which are often used interchangeably, actually contain completely different types of...
Shared Facility Spotlight: Pluripotent Stem Cell Facility
By CincinnatiChildrens.org - Cincinnati Children’s Pluripotent Stem Cell Facility (PSCF) facilitates and supports research using human pluripotent stem cells (hPSCs). HPSCs are generated from a skin biopsy or blood sample that can be obtained from any patient and,...
Engineered stem cells target autoimmune diseases
By Adam Boros, PhD - Drug Discovery News - Genetically modified stem cells show promise in a targeted approach to taming inflammation in autoimmune diseases. Researchers developed an immunotherapy using chimeric antigen receptors and mesenchymal stromal cells, paving...
BioXtek: Creating cutting-edge regenerative therapeutics from human birth tissue
by Phil Newman - Longevity.Technology - At birth, the baby is the headline event while the rest of the materials, which have played a crucial role in the intricate process of building a fully-functioning human from just two cells, are often discarded as medical waste....
Scientists create a cell that precludes malignant growth
By University of Helsinki - Phys.org - Cell therapies could help in the treatment of hereditary diseases, myocardial infarction and hundreds of other diseases. For many blood diseases, new cells can already be transplanted into human patients, and diabetes has also...
A patch fitted with stem cells helps repair damaged spinal cords
by Clara Rodriguez Fernandez - Advanced Science News - Scientists have taken a step closer toward a treatment to repair damaged spinal cord tissue with a wireless patch that delivers electrical pulses to stem cells. The device could overcome some major hurdles in the...
Prime Editing Corrects Cystic Fibrosis Mutation
by Gorm Pamgren - CRISPR Medicine News - Researchers have refined prime editing (PE) to correct the cystic fibrosis (CF) related gene CFTR. Results demonstrated improved efficiency and minimal off-target effects in correcting the F508del mutation in human airway...
Trial of cell-based therapy for high-risk lymphoma leads to FDA breakthrough designation
By Science Daily News - CAR-T cell therapy helps some with intractable lymphoma, but those who relapse have few options. Modifying the therapy's molecular target improved response. Source: Stanford Medicine. Click Here to read the article