NEWS and OPINIONS

A CRISPR Tool for Tinkering with the Human Transcriptome

A CRISPR Tool for Tinkering with the Human Transcriptome

By Danielle Gerhard, PhD - The Scientist - ike the find-and-replace feature of a word processor, CRISPR-based engineering allows scientists to quickly and efficiently edit DNA sequences with base pair precision. Lauded as the great democratizer of gene editing, CRISPR...

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Shared Facility Spotlight: Pluripotent Stem Cell Facility

Shared Facility Spotlight: Pluripotent Stem Cell Facility

By CincinnatiChildrens.org - Cincinnati Children’s Pluripotent Stem Cell Facility (PSCF) facilitates and supports research using human pluripotent stem cells (hPSCs). HPSCs are generated from a skin biopsy or blood sample that can be obtained from any patient and,...

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Engineered stem cells target autoimmune diseases

Engineered stem cells target autoimmune diseases

By Adam Boros, PhD - Drug Discovery News - Genetically modified stem cells show promise in a targeted approach to taming inflammation in autoimmune diseases. Researchers developed an immunotherapy using chimeric antigen receptors and mesenchymal stromal cells, paving...

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Scientists create a cell that precludes malignant growth

Scientists create a cell that precludes malignant growth

By University of Helsinki - Phys.org - Cell therapies could help in the treatment of hereditary diseases, myocardial infarction and hundreds of other diseases. For many blood diseases, new cells can already be transplanted into human patients, and diabetes has also...

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Prime Editing Corrects Cystic Fibrosis Mutation

Prime Editing Corrects Cystic Fibrosis Mutation

by Gorm Pamgren - CRISPR Medicine News - Researchers have refined prime editing (PE) to correct the cystic fibrosis (CF) related gene CFTR. Results demonstrated improved efficiency and minimal off-target effects in correcting the F508del mutation in human airway...

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