NEWS and OPINIONS
Universal plug-and-play CAR-T cell therapy could transform cancer immunotherapy
by University of Chicago Medical Center - MedicalXpress - Researchers at the University of Chicago have developed a "universal" chimeric antigen receptor (CAR) platform that offers enhanced safety, adaptability, and the potential to overcome long-standing barriers in...
Stopping time in cells exposes life’s fastest secrets
By The University of Osaka - Science Daily - Researchers from The University of Osaka develop time-deterministic cryo-optical microscopy, which freezes cells with millisecond precision, enabling accurate, high-resolution visualization of transient moments during...
Stanford Breakthrough: Stem Cell Transplants Without Toxic Chemo or Radiation
By By Erin Digitale, Stanford Medicine - SciTechDaily - A Phase 1 clinical trial has shown that an antibody developed at Stanford Medicine can prepare patients for stem cell transplantation while avoiding toxic side effects. A phase 1 clinical trial has demonstrated...
World’s first spinal cord transplant to take place in Israel, could allow patients to walk again
By PESACH BENSON/TPS - The Jerusalem Post - Tel Aviv University announced on Wednesday that the surgery will take place in Israel, marking a historic milestone in regenerative medicine. Israel is preparing to perform the world’s first-ever human spinal cord implant...
Stem cell-derived dopamine neurons improve depression-like behaviors in mice
by Justin Jackson - Phys.org - MedicalXpress - The Institute of Neuroscience, Chinese Academy of Sciences, reports that human stem cell-derived A10-like midbrain dopaminergic neurons integrate into mouse mesocorticolimbic circuits and suppress anxiety and depression...
New activated cell therapy to treat osteoarthritis
By Sarah Nesbella - Colorado State University - Osteoarthritis (OA) affects over 550 million people worldwide, and there still aren’t effective treatments to stop the continued joint inflammation and cartilage destruction caused by OA. The lifetime likelihood of...
In cell therapy, cost is a hot issue. The industry might need a cold solution.
by Michael Gibney - PharmaVoice - The first cell therapy approved by the FDA, Dendreon’s Provenge for prostate cancer, had a bumpy start on the market in 2010, as the autologous treatment was logistically difficult to manufacture and administer, and thus also to...
Stem cell discovery could be key to healing tough-to-fix fractures
By Penn Medicine - The ability of a newly understood stem cell originating in skeletal muscle to turn into bone could hold the key to bone healing after catastrophic fractures. When bones break and there is extreme tissue loss—such as after a car accident or a...
USAMRIID scientists develop novel 3D bioprinted tissue model
by Quentin Johnson - dvidshub.net - FORT DETRICK, Md.– Scientists at the U.S. Army Medical Research Institute of Infectious Diseases have successfully created a novel 3D bioprinted vascular liver tissue model, marking a significant advancement in biomedical research...
ARPA-H data chief departs over disagreement with mRNA vaccine rollback
By Darren Incorvaia - Fierce Biotech - After the Department of Health and Human Services canceled about $500 million in funding for mRNA vaccine development, one senior agency leader has decided to call it quits. Alastair Thomson is resigning as chief data officer at...
Trained human bone marrow mesenchymal stem cells restore tissue immuno-microenvironment in fulminant hepatic failure mice
By BMC - Part of SpringerNature - Trained immunity with human bone marrow mesenchymal stem cells (hBMSC) is a promising approach to liver regeneration. This study aimed to clarify the trained-hBMSC (T-hBMSC) in restoring tissue immuno-microenvironment in fulminant...
Barcelona Biobank Gets Grant To Research Stem Cell Reprogramming in Wild Animals
By Technology Networks - The Barcelona CryoZoo aims to safeguard and study biological material from a wide range of animal species. The Barcelona CryoZoo is a one-of-a-kind project aiming to safeguard and study biological material from a wide range of animal species –...