NEWS and OPINIONS
CAR NK cell therapy clinical trial puts follicular lymphoma survivor into remission
By Cynthia DeMarco - MD Anderson Cancer Center - When JC Cox was diagnosed with a type of non-Hodgkin lymphoma called follicular lymphoma in 2006, the now-retired HVAC technician sought treatment close to his home in Dallas. But several rounds of strong chemotherapy...
Stem cell therapy linked to lower risk of heart failure after a heart attack
By BMJGroup - Technique may be a valuable add-on procedure for patients with weak heart function after a heart attack, say researchers Patients with weak heart function who receive stem cell therapy shortly after a heart attack are at lower risk of developing heart...
Embryo-Like ‘Blood Factories’ Could One Day Supplement Donations
By Jess Cockerill - Science Alert - Clusters of cells grown in the lab have been encouraged to produce human blood stem cells in a discovery that could one day supplement donations to people with blood disorders like leukemia and lymphoma. The University of...
Long-Term Growth Hormone Therapy Boosts Pediatric Stem Cells
by Bioenginee.org - In a groundbreaking study published in Scientific Reports, researchers have unveiled significant findings surrounding the long-term effects of growth hormone therapy in pediatric patients suffering from growth hormone deficiency. This research is...
New UCLA drug could restore heart and organ function
By Drug Target Review - UCLA researchers have developed a monoclonal antibody, AD-NP1, that blocks ENPP1 to enhance heart repair and reduce scar tissue. Injuries like cuts to the skin tend to heal naturally, but damage to internal organs like the heart or kidneys...
Parkinson’s treatment tested at UW showing promise in first clinical trial
By Chris Barncard - University of Wisconsin News - Parkinson’s patients are receiving a new investigational treatment after a successful study at the University of Wisconsin–Madison helped demonstrate the cell therapy’s safety in non-human primates and refine the...
Scientists Create Early Human Embryos From Skin Cells And Sperm
By StudyFinds Analysis - Researchers have created human embryos by taking nuclei from ordinary skin cells, placing them into donated eggs, and fertilizing them with sperm. The work is a laboratory demonstration that shows what might eventually be possible for people...
This “chaos enzyme” may hold the key to stopping cancer spread
By Science Daily - A Weill Cornell Medicine team has found that triple-negative breast cancer depends on the enzyme EZH2 to spread. By silencing key genes, EZH2 drives chaotic cell divisions and fuels metastasis. Blocking EZH2 restored stability and prevented cancer...
New Tool Identifies Proteins That Control Gene Activity
by Weill Cornell Medicine - he SCOPE system can capture proteins binding to regions of DNA that control gene expression. The illustration depicts part of the process where a small guide RNA delivers a protein bearing a special amino acid to the desired region....
Takeda Exits Cell Therapy Amid Strategic Pivot, Dealing Blow to Once Promising Modality
by Tristan Manalac - BioSpace - Takeda is looking to offload its cell therapy platform and preclinical assets to a yet-unidentified external partner. 137 employees will be let go as part of the move. Takeda will no longer invest in cell therapies moving forward as the...
New CAR T therapy targets solid tumours safely and effectively
By Drug Target Review - USC researchers have engineered CAR T cells to deliver a dual protein therapy that targets solid tumours – offering hope for cancers previously resistant to treatment. Chimeric antigen receptor (CAR) T-cell therapy, which uses a patient’s own...
High-throughput 3D engineered paediatric tumour models for precision medicine
By Molecular Systems Biology - Abstract Precision medicine for paediatric and adult cancers that incorporates drug sensitivity profiling can identify effective therapies for individual patients. However, obtaining adequate biopsy samples for high-throughput (HTP)...