NEWS and OPINIONS
Interviews of 2025: The Big Issues
By Danny Sullivan - Longevity.Technology - Healthspan as a universal right, the need for new regulation, the age of mitochondrial therapies and 7 shifts to accelerate longevity. As we reflect on some of the interviews we’ve conducted over the past 12 months, it’s...
Novel surgical approach for retinal gene therapy shows promise
By Mayo Clinic - A Mayo Clinic study published in the September 2025 issue of Science Advances explores a novel approach to retinal gene therapy using fibrin hydrogels encapsulating adeno-associated virus 2-green fluorescent protein (AAV2-GFP). The findings suggest a...
UC Irvine receives $12 million to test novel stem cell therapy for Huntington’s disease
By UCI Health News - CIRM award will support first-of-its-kind clinical trial in humans This award will support a first-in-human safety and tolerability study of an embryonic stem cell-derived neural stem cell product for Huntington’s disease, a milestone for patients...
To Bring Cell Culture into the Future, Consider Microenvironments
by James Lim, PhD - The Scientist - Let’s face it: Nobody pursues a career in science for the joy of culturing cells. But this thankless and time-intensive task is the backbone of biological research. When it’s done extremely well, the results generated from...
Case Study: Patient Remains Disease Free Five Years After Allogenic CAR T-Cell Therapy
By Cleveland Clinic - Patient with quadruple refractory multiple myeloma achieves complete response with cell therapy A Cleveland Clinic patient participated in a clinical trial of allogenic CAR T-cell therapy to treat highly resistant multiple myeloma and achieved a...
The quest to slow aging leads scientists into the powerhouse of cells
by Mark Johnson - MSN - Aging taps us on the shoulder in many ways: wrinkles, thinning hair, loss of flexibility, slowing of the brain. But the process also unfolds at a more fundamental, microscopic level, as the energy source inside most cells deteriorates....
Disarming cancer stem cells’ shield makes immunotherapy more effective
by UChicagoMedicine - Immunotherapy has revolutionized cancer care by training the immune system to detect and destroy tumors. For many patients, it works very well in shrinking tumors and sending cancer into remission, an undetectable state of cancer. But that...
Regeneron’s experimental therapy combo effective in untreated cancer patients
By Sriparna Roy - Reuters News - Regeneron (REGN.O), opens new tab said on Saturday its experimental cancer combination therapy was effective and showed disappearance of the disease in previously untreated patients with a type of blood cancer in the first part of a...
The Best Biomarkers For Longevity, According To Experts
By Heidi Borst - Forbes - Human longevity has reached new heights. During the 20th century, lifespan in high-income countries increased by about 30 years due to public health and medicine advancements, according to a 2024 analysis in Nature Aging.[1] In the U.S., the...
The world’s first personalized gene therapy
By Cold Spring Harbor Laboaratory - How does science make life better? Here’s one example spanning eons. There’s an adaptive immune system called CRISPR that has existed in bacteria for billions of years. Thanks to fundamental biology research, it is now being used to...
Nanoflowers rejuvenate old and damaged human cells by replacing their mitochondria
by James Cavin - Phys.org - Biomedical researchers at Texas A&M University may have discovered a way to stop or even reverse the decline of cellular energy production—a finding that could have revolutionary effects across medicine. Dr. Akhilesh K. Gaharwar and...
CRISPR Gets an Invisibility Cloak
By Technology Networks - Scientists created an immunity-proof CRISPR system that reveals hidden metastasis genes in mouse tumour models. The immune system plays a crucial role in fighting tumours and metastases. Consequently, it is decisive to conduct cancer research...