By Stem Cells Translational Medicine - Background The objective of this study was to assess the long-term effectiveness and safety of implanting mesenchymal stem cells derived from umbilical cord tissue (UC-MSC) in patients diagnosed with retinitis pigmentosa (RP)....

By Drug Target Review - CAR T therapies are saving lives, but toxicities such as CRS and ICANS remain a major barrier. What will it take to overcome them? Chimeric antigen receptor (CAR) T-cell therapy is changing lives for patients with hard-to-treat cancers. By...

by University of Geneva - MedicalXpress - Transplanting hematopoietic stem cells from healthy individuals is one of the possible treatments for blood cancers. In Switzerland, it involves nearly 300 patients per year. However, nearly half of transplants fail, mainly...

By Journal of Drug Delivery Science and Technology - Abstract Wound healing is the process of tissue regeneration, which, under normal conditions, is a very time-consuming process. It is also very susceptible to complications such as infection and chronic...

By By Tiare Dunlap, University of California - SciTechDaily - Antidepressants help immune cells fight cancer. They may improve therapy effectiveness. A commonly prescribed antidepressant may also strengthen the body’s defenses against cancer, according to new research...

by Alejandra Manjarrez, PhD - Exploring Drug Discovery and Development = Macrophage-based therapies for liver cirrhosis are entering clinical trials, but key challenges remain before they become a viable treatment. Macrophages — key players of the immune system —...

By UC San Diego Today - Findings reveal space-induced genetic, mitochondrial and inflammatory stress in blood-forming stem cells, offering insight into aging and risk of disease during long-duration space travel. Researchers from University of California San Diego...

by Andrea Lius, PhD - The Scientist - Researchers bank on stem cells to study developmental biology, understand oral cancer, regenerate organs, and save species on the brink of extinction. Stem cells can self-renew and differentiate into a wide variety of cell types,...

by University of Chicago Medical Center - MedicalXpress - Researchers at the University of Chicago have developed a "universal" chimeric antigen receptor (CAR) platform that offers enhanced safety, adaptability, and the potential to overcome long-standing barriers in...

By The University of Osaka - Science Daily - Researchers from The University of Osaka develop time-deterministic cryo-optical microscopy, which freezes cells with millisecond precision, enabling accurate, high-resolution visualization of transient moments during...

By By Erin Digitale, Stanford Medicine - SciTechDaily - A Phase 1 clinical trial has shown that an antibody developed at Stanford Medicine can prepare patients for stem cell transplantation while avoiding toxic side effects. A phase 1 clinical trial has demonstrated...

By PESACH BENSON/TPS - The Jerusalem Post - Tel Aviv University announced on Wednesday that the surgery will take place in Israel, marking a historic milestone in regenerative medicine. Israel is preparing to perform the world’s first-ever human spinal cord implant...