NEWS and OPINIONS

Designer Stem Cells Power New R&D Assay Systems
by By Kathy Liszewski - Genetic Engineering & Biology News - Novel allogeneic stem cells and differentiated iPSCs are providing more physiologically relevant disease models From axolotls to zebrafish, stem cells possess remarkable regenerative abilities, enabling them...

Slashing NIH funding imperils the foundation of medical research
By Bobby Mukkamala, MD - AMA - For more than a century, NIH-sponsored research has played a critical role in improving the nation’s health. This vital work must continue. It’s not hyperbole to say my sudden brain cancer diagnosis last fall could have put a swift end...

Mayo Clinic treats first person in the US with a novel radiopharmaceutical therapy for breast cancer
by Brittany Cordeiro - Mayo Clinic - ROCHESTER, Minn. — Mayo Clinic has treated the first person in the U.S. using a novel radioactive medicine for advanced breast cancer as part of an international multisite clinical trial. The medicine used in this clinical trial...

Novel, Less Toxic, Stem Cell Transplant Prep Yields Successful Outcomes
By Genectic Engineering & Biotechnology - Phase I clinical trial results suggest that an antibody treatment, used in combination with other drugs, enabled stem cell transplants for three children with Fanconi anemia without toxic busulfan chemotherapy or radiation....

Adipose-derived mesenchymal stromal/stem cells in type 1 diabetes treatment
By Nature Communications Biology - Adipose tissue-derived mesenchymal stromal/stem cells (ADMSCs) represent a novel therapeutic intervention for Type 1 Diabetes (T1D). The attractiveness of ADMSCs is characterized by their immunomodulatory activities, regenerative...

Sarepta fails to win EU backing for muscle disorder gene therapy
By Christy Santhosh - Reuters News - Sarepta Therapeutics (SRPT.O), failed to win the European drug regulator's backing for its muscle disorder gene therapy on Friday, as the company faces intense regulatory scrutiny after two recent patient deaths tied to the...

The pandemic aged our brains, whether we got Covid or not, study find
By Linda Carroll NBC News - Brain aging may have sped up during the pandemic, even in people who didn’t get sick from Covid, a new study suggests. Using brain scans from a very large database, British researchers determined that during the pandemic years of 2021 and...

Florida Is Now a Haven for Unproven Stem-Cell Treatments
By Emily Mullin - WIRED - Florida is the latest state to sidestep the authority of the Food and Drug Administration by allowing patients to access certain stem-cell treatments that have not been rigorously evaluated and approved. Under a new law that went into effect...

Stem cell therapy found to boost fertility in women with ovarian failure
By Celeste Krewson - Contemporary OB/GYN - Stem cell treatment may be effective for fertility restoration in women with ovarian failure, according to a recent study published in Aging (Aging-US).1 This method was associated with a 70% oocyte activation rate and...

3D Bioprinting: How The Future of Medicine is Being Built, Layer by Layer
By Kevin Famuyiro - The Los Angeles Times - For years it’s been science fiction: printing a spare part for the human body on demand. But today in labs around the world that fiction is becoming a reality. 3D bioprinting, the marriage of biology and engineering, allows...

Ankles may hold the key to new osteoarthritis therapy
by Duke University - Futurity - The ankle’s ability to regenerate cartilage uses the same mechanisms that enable some animals to grow new limbs, and it could be harnessed to repair cartilage in knees and hips hobbled by osteoarthritis. Those findings in the journal...

Engineering immune cells within the body
By National institutes of Health - Chimeric antigen receptor (CAR) T cell therapies involve taking immune cells, called T cells, from a patient and engineering them to make a protein that lets them recognize and attack the patient’s cancer cells. CAR T cells have...