By Lei Lei Wu - EndpointsNews MIT scientists have developed a tool that they say can insert large gene sequences where they want in the genome. In a paper published Thursday in Nature Biotechnology, MIT fellows Omar Abudayyeh, Jonathan Gootenberg and colleagues detail...

By Sulagna Ghosh, Ralda Nehme & Lindy E. Barrett Nature Communications While there are a growing number of human pluripotent stem cell repositories, genetic diversity remains limited in most collections and studies. Here, we discuss the importance of incorporating...

By Max Delbrook Center A big step toward producing rhino gametes To save the northern white rhinoceros from extinction, the BioRescue team is racing to create lab-grown egg and sperm cells of the critically endangered subspecies. The team has now reported a milestone...

by Bob Yirka , Phys.org A team of researchers at the University of California, Berkeley, and University of California, Los Angeles, working with a colleague from Vilnius University, has found evidence of thousands of phages with DNA strands that should allow them to...

By Megan Molteni - Stat News He Jiankui, the Chinese biophysicist who created the first gene-edited children, had been quiet since completing a three-year prison sentence in April, leaving many to wonder whether he had plans to return to scientific research. Earlier...

By Penn Today Penn Medicine researchers laud the early results for CAR T therapy in lupus patients, which point to broader horizons for the use of personalized cellular therapies. Engineered immune cells, known as CAR T cells, have shown the world what personalized...

by Rameesha Sajwar - Wonderful Engineering Gene-editing technology CRISPR has been used to remove genes from immune system cells to make them better at fighting cancer. Recently, PACT Pharma and UCLA have used CRISPR to remove and add genes to these cells to help them...

CIRM-funded USC+CHLA Alpha Clinic boosts capacity for clinical and translational research, community outreach, training and manufacturing By Wayne Lewis - Keck School of Medicine of USC The California Institute for Regenerative Medicine (CIRM), the state’s stem cell...

by Kelsey A. Rankin, Alison Mosier-Mills, Walter Hsiang & Daniel H. Wiznia - BMC Archives of Public Health Abstract Secret shopper studies are particularly potent study designs that allow for the gathering of objective data for a variety of research hypotheses,...

by by Kerstin Wagner, Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut e.V. (FLI) - Phys.org Image: Hematopoietic stem cells age very heterogeneously. The TAZ protein, a co-activator of the Hippo signaling pathway, can protect blood stem cells from...

by Takahiro Tanimoto, Kentaro Endo, Yuriko Sakamaki, Nobutake Ozeki, Hisako Katano, Mitsuru Mizuno, Hideyuki Koga & Ichiro Sekiya - Scientific Reports Abstract The possibility that mesenchymal stem cells (MSCs) can adhere to partial defects or degenerative areas in...

By By Cade Hildreth, BioInformant Palo Alto, CA – Greenstone Biosciences, Inc. (“Greenstone Bio”), a commercial-stage computational biology company, announces that the Company has received a DISC0 grant funding from the California Institute of Regenerative Medicine...