NEWS and OPINIONS
Case Study: Patient Remains Disease Free Five Years After Allogenic CAR T-Cell Therapy
By Cleveland Clinic - Patient with quadruple refractory multiple myeloma achieves complete response with cell therapy A Cleveland Clinic patient participated in a clinical trial of allogenic CAR T-cell therapy to treat highly resistant multiple myeloma and achieved a...
The quest to slow aging leads scientists into the powerhouse of cells
by Mark Johnson - MSN - Aging taps us on the shoulder in many ways: wrinkles, thinning hair, loss of flexibility, slowing of the brain. But the process also unfolds at a more fundamental, microscopic level, as the energy source inside most cells deteriorates....
Disarming cancer stem cells’ shield makes immunotherapy more effective
by UChicagoMedicine - Immunotherapy has revolutionized cancer care by training the immune system to detect and destroy tumors. For many patients, it works very well in shrinking tumors and sending cancer into remission, an undetectable state of cancer. But that...
Regeneron’s experimental therapy combo effective in untreated cancer patients
By Sriparna Roy - Reuters News - Regeneron (REGN.O), opens new tab said on Saturday its experimental cancer combination therapy was effective and showed disappearance of the disease in previously untreated patients with a type of blood cancer in the first part of a...
The Best Biomarkers For Longevity, According To Experts
By Heidi Borst - Forbes - Human longevity has reached new heights. During the 20th century, lifespan in high-income countries increased by about 30 years due to public health and medicine advancements, according to a 2024 analysis in Nature Aging.[1] In the U.S., the...
The world’s first personalized gene therapy
By Cold Spring Harbor Laboaratory - How does science make life better? Here’s one example spanning eons. There’s an adaptive immune system called CRISPR that has existed in bacteria for billions of years. Thanks to fundamental biology research, it is now being used to...
Nanoflowers rejuvenate old and damaged human cells by replacing their mitochondria
by James Cavin - Phys.org - Biomedical researchers at Texas A&M University may have discovered a way to stop or even reverse the decline of cellular energy production—a finding that could have revolutionary effects across medicine. Dr. Akhilesh K. Gaharwar and...
CRISPR Gets an Invisibility Cloak
By Technology Networks - Scientists created an immunity-proof CRISPR system that reveals hidden metastasis genes in mouse tumour models. The immune system plays a crucial role in fighting tumours and metastases. Consequently, it is decisive to conduct cancer research...
The vital, overlooked role of body fat in shaping your health and mind
By Linda Geddes - NewScientist - f you melted down the average UK adult, you’d find around 22 kilograms (48.5 pounds) of creamy yellow fat – equivalent to around 88 blocks of lard, enough to fill two-thirds of a small suitcase or cast into 446 dinner candles. Melted,...
Crispr gene-editing technology offers new hope for HIV cure but faces delivery challenges
By Tosin Thompson - Chemistry World - Two years ago, the UK became the first country to approve Casgevy, a Crispr-based therapy for the blood disorders sickle cell disease and β-thalassaemia. This year saw the world’s first personalised Crispr therapy for a baby boy...
Vycellix Prepares for First-in-Human Study of Novel Allogeneic Cell Therapy Powered by Its Universal Cell Engineering Platform
By Vycellix - - Single-step CD45-engager technology shows robust immune evasion with functional persistence in pre-clinical models - Phase 1 study to evaluate ‘off-the-shelf’ natural killer cell cancer immunotherapy in the treatment of multiple myeloma BOCA RATON,...
Scientists use stem cells to model rare genetic blindness in children
by Children's Medical Research Institute - MedicalXpress - Researchers at the Eye Genetics Research Unit at Children's Medical Research Institute (CMRI) are the first in the world to use stem cells to study one of the genetic causes of Leber Congenital Amaurosis...