NEWS and OPINIONS

Bone Marrow Banking Boosts Life-Saving Cell Therapy Development
by The Scientist - Stem cells form the backbone of many cell-based therapies due to their unique properties, including the ability to self-renew and differentiate to many cell types. Multiple cell therapies deliver exogenous bone marrow stem cells into patients, which...

Experts explore the future of iPSC-based cell therapies
By Drug Target Review - Regenerative medicine is set to be transformed by induced pluripotent stem cells (iPSCs). These versatile cells can be reprogrammed to become virtually any cell type in the human body, offering groundbreaking possibilities for treating a wide...

Disruption of a single amino acid in a cellular protein makes breast cancer cells behave like stem cells
By Queen Mary University of London - New research led by Queen Mary’s Institute of Dentistry has found that changes to the intermediate filament (IF) protein, vimentin, were found to promote tumour growth. Vimentin is a type III intermediate filament (IF) protein...

Stem Cells in the Brain Use Childlike Signals to Trigger Regeneration
By Neuroscience News - Scientists have discovered that neural stem cells (NSCs) receive constant feedback from their daughter cells, influencing whether they remain dormant or activate to form new neurons and glia. This parent-child relationship helps regulate brain...

3D microgel device puts stem cells under pressure
Robert Lea - Advanced Science News - Scientists have developed a new 3D cell culture device made from soft, porous microgel particles that can mimic the effects of pressure on stem cells. This platform allows researchers to study and even influence how stem cells...

Assessment of immune modulation strategies to enhance survival and integration of human neural progenitor cells in rodent models of spinal cord injury
By Stem Cells Translational Medicine - Our study demonstrates the advantage of using genetically immunodeficient rodents over traditional pharmacological methods in cell therapy research for spinal cord injury (SCI). This approach preserves the integrity and...

Christopher Reeve’s daughter describes the simple, ‘beautiful’ way Robin Williams showed up for her dad
By Dan Heching -CNN - While a lot has been said about the friendship between Robin Williams and Christopher Reeve, the famed pair’s bond illustrates a very basic and instrumental type of kindness, according to Reeve’s daughter. In a recent interview with CNN,...

Penn researchers develop temperature-sensitive protein with applications in cancer cell therapy
By Megan Liu - The Daily Pennsylvanian - A group of Penn scientists has developed a new method to remotely control engineered cells inside the human body using heat. Led by bioengineer Lukasz Bugaj, the innovation introduces a temperature-sensitive protein called...

Enhanced bone regeneration using mesenchymal stem cell-loaded 3D-printed alginate-calcium Titanate scaffolds: A Calvarial defect model study
By Science Direct - This study investigates the efficacy of a 3D-printed alginate composite scaffold enriched with calcium titanate nano powders and loaded with mesenchymal stem cells (MSCs) for bone regeneration in a calvarial defect model. Scaffolds (20 mm × 20 mm ×...

New study shows stem cell therapy ‘jump-start’ brain repair after stroke
by Gladstone Institutes - MedicalXpress - Every 40 seconds, someone in the United States has a stroke. For survivors of the most common type of stroke, called an ischemic stroke, only about 5 percent fully recover. Most others suffer from long-term problems, including...

Tailoring cell therapies for diabetic metabolic phenotypes: a comparative study on the efficacy of various umbilical cord-derived cell regimens
By Stem Cells Translational Medicine Given the high heterogeneity of type 2 diabetes mellitus (T2DM), it is imperative to develop personalized stem cell infusion regimen for targeted metabolic phenotype in order to ensure optimal therapeutic efficacy. In this study,...

Researchers Make Breakthrough in Bioprinting Functional Human Heart Tissue
By Technology Networks - Researchers at University of Galway have developed a way of bioprinting tissues that change shape as a result of cell-generated forces, in the same way that it happens in biological tissues during organ development. The breakthrough science...