NEWS and OPINIONS
The Quest to Cure Myeloma: Mission Accomplished?
by Charles Bankhead - MedPageToday - Long-term survival in the CARTITUDE-1 trial showed that almost half of patients remained, alive with a median overall survival (OS) of 60.7 months. Almost three-fourths of the survivors remained progression free, and more than a...
This CRISPR breakthrough turns genes on without cutting DNA
by University of New South Wales - Science Daily - A new CRISPR breakthrough shows scientists can turn genes back on without cutting DNA, by removing chemical tags that act like molecular anchors. The work confirms these tags actively silence genes, settling a...
Stanford Medicine study shows why mRNA COVID-19 vaccine can cause myocarditis
By Bruce Goldman - Stanford Medicine - Stanford Medicine investigators have unearthed the biological process by which mRNA-based vaccines for COVID-19 can cause heart damage in some young men and adolescents — and they’ve shown a possible route to reducing its...
How Our Own Cells Could Implant The Next Generation Of Nonsurgical Brain Microchips
By William A. Haseltine, - Forbes - Treating brain diseases is extraordinarily challenging, because drugs often work poorly and implants require risky surgery that can jeopardize critical brain functions. A group at MIT has sought a different approach, using the...
Melanoma cancer cells secrete extracellular vesicles to paralyze immune cells
by Tel-Aviv University - MedXpress - A new international study led by Prof. Carmit Levy of the Department of Human Genetics and Biochemistry at the Gray Faculty of Medical & Health Sciences at Tel Aviv University finds that melanoma cancer cells paralyze immune...
Engineered Dendritic Cells Harness Tumor EVs to Boost Cancer Immunotherapy
By Genetic Engineering adn Biotechnology News - Cancer immunotherapy transforms a patient’s immune cells into a “search‑and‑destroy” force against tumors. But many cancers learn to camouflage themselves from dendritic cells—the immune system’s scouts—making them...
Top FDA Gene and Cell Therapy News: 2025 Year-End Recap
By Matt Hoffman - CGTlive - As 2025 comes to a close, CGTLive has looked back on some of the most-read and most impactful FDA regulatory decisions and news in the cell and gene therapy space. These approvals and regulatory actions marked major progress for patients...
Fatal Complication of Stem Cell Transplants Gets Its First FDA-Approved Therapy
By Frank Vinluan - MedCity News - A rare but severe stem cell transplant complication that often becomes fatal now has its first FDA-approved treatment, a therapy developed by biotechnology company Omeros. Omeros’s complement system drug Yartemlea is now FDA approved...
The 98% mystery: Scientists just cracked the code on “junk DNA” linked to Alzheimer’s
by Science Daily - Researchers have revealed that so-called “junk DNA” contains powerful switches that help control brain cells linked to Alzheimer’s disease. By experimentally testing nearly 1,000 DNA switches in human astrocytes, scientists identified around 150...
New method preserves iPS cells for regenerative medicine
By Drug Target Review - Kobe University researchers have developed a new way of freeze induced pluripotent stem cells (iPS cells) directly in their culture dishes without losing viability or pluripotency. Researchers at Kobe University have developed a novel method...
MIT Scientists Have Discovered a Way To Rejuvenate the Immune System
By Anne Trafton, Massachusetts Institute of Technology - ScitTechDaily - As the immune system weakens with age, researchers have found a way to temporarily boost its function by reprogramming liver cells to support T-cell development. As people get older, the immune...
Lab-Grown Brain Tissue Finally Wires Itself Thanks to Crystal-Loaded Microgels
by ScienceBlog - Researchers at the University of Illinois Urbana-Champaign have engineered a solution using tiny microgels packed with antioxidant crystals. Published in Advanced Functional Materials, their work demonstrates how a single dose of these protective...