NEWS and OPINIONS
Discoveries from human stem cell research in space that are relevant to advancing cellular therapies on Earth
By Fay Ghani, Abba C. Zubair - Nature - Stem cell research performed in space has provided fundamental insights into stem cell properties and behavior in microgravity including cell proliferation, differentiation, and regeneration capabilities. However, there is...
Zebrafish use surprising strategy to regrow spinal cord
by Julia Evangelou Strait - Washington University College of Medicine - Detailed blueprint of nerve cells’ dramatic changes could help identify ways to heal spinal cord damage. Zebrafish are members of a rarefied group of vertebrates capable of fully healing a severed...
New way to extend ‘shelf life’ of blood stem cells will improve gene therapy
By University of Cambridge - Researchers have discovered a way to extend the shelf life of blood stem cells outside the body for use in gene therapy, providing patients with better options and improving their outcomes. We were able to identify a key molecular...
Understanding the Risk of Second Cancers After CAR T-Cell Therapy
By The National Cancer Institute - In November 2023, the Food and Drug Administration announced that it was investigating more than 20 instances of second cancers—specifically, T-cell lymphomas—in people who had been treated with CAR T-cell therapies. In several...
Astrocytes Are a Key Player in the Awakeneing of Dormant Neural Stem Cells
By Technology Networks - Research offers new hope for treating neurodevelopmental disorders by activating dormant neural stem cells. Scientists from Duke-NUS Medical School and the Mechanobiology Institute (MBI) at the National University of Singapore (NUS) have...
UofL cardiologist leading clinical trial for high potential new therapy for heart failure
By University of Louisville School of Medicine - A new stem cell therapy for heart failure is being tested in patients at the University of Louisville and UofL Health. The trial is the first in the U.S. to test umbilical cord-derived stem cells in patients for heart...
Next-generation CRISPR-based gene-editing therapies tested in clinical trials
By Natalie Healey - Nature Medicine Going from the laboratory to an approved therapy in 11 years is no mean feat. That is the story of the world’s first approved CRISPR–Cas9 therapy, greenlit by the US Food and Drug Administration in December 2023....
First Engineered T Cell Therapy for Solid Tumors Approved by the FDA
By Inside Precision Medicine - The immunotherapy afamitresgene autoleucel (afami-cel) for the treatment of adults with the rare soft tissue cancer called synovial sarcoma was granted accelerated approval late last week by the U.S. Food and Drug Administration (FDA)....
Researchers decipher new molecular mechanisms related to biological tissue regeneration
By University of Barcelona - A study published in The EMBO Journal opens new perspectives to better understand how the molecular mechanisms involved in regenerative medicine work. The study focuses on tumour necrosis factor-α (TNF-α) and its receptors TNFR, molecules...
Rapid Stem Cell Model Advances Parkinson’s Research
By Neuroscience News - Researchers have developed a model that quickly converts stem cells to brain cells with Parkinson’s disease (PD) protein structures, allowing for personalized study and treatment. This new approach can transform stem cells into brain cells...
Breaking the Chains: How CRISPR Gene Therapy Gave Victoria Gray a New Life
by Molly Coddington - Technology Networks - Like many young girls in elementary school, Victoria Gray wanted to be a cheerleader, until she was told by her doctor that this simply wouldn’t be possible; the exertion placed on her body by the training regimen could have...
Detecting pancreatic cancer through changes in body composition and metabolism
by Marla Broadfoot, Ph.D. - Mayo Clinic - Pancreatic cancer is a formidable disease, often diagnosed too late for effective treatment. However, new research from Mayo Clinic represents a promising step toward identifying biological signals or biomarkers that may aid...