By Science Daily - A Weill Cornell Medicine team has found that triple-negative breast cancer depends on the enzyme EZH2 to spread. By silencing key genes, EZH2 drives chaotic cell divisions and fuels metastasis. Blocking EZH2 restored stability and prevented cancer...

by Weill Cornell Medicine - he SCOPE system can capture proteins binding to regions of DNA that control gene expression. The illustration depicts part of the process where a small guide RNA delivers a protein bearing a special amino acid to the desired region....

by Tristan Manalac - BioSpace - Takeda is looking to offload its cell therapy platform and preclinical assets to a yet-unidentified external partner. 137 employees will be let go as part of the move. Takeda will no longer invest in cell therapies moving forward as the...

By Drug Target Review - USC researchers have engineered CAR T cells to deliver a dual protein therapy that targets solid tumours – offering hope for cancers previously resistant to treatment. Chimeric antigen receptor (CAR) T-cell therapy, which uses a patient’s own...

By Molecular Systems Biology - Abstract Precision medicine for paediatric and adult cancers that incorporates drug sensitivity profiling can identify effective therapies for individual patients. However, obtaining adequate biopsy samples for high-throughput (HTP)...

By Grace Huckins - MIT Technology Review - Imagine this: You’ve been feeling unwell, so you call up your doctor’s office to make an appointment. To your surprise, they schedule you in for the next day. At the appointment, you aren’t rushed through describing your...

By Stem Cells Translational Medicine - Introduction While lung research has made great strides in understanding lung physiology, lung pathology still presents a major burden to patients and healthcare systems globally. To develop new effective therapeutics to improve...

By Alison Satake - Mayo Clinic - More than 4 million people worldwide have end-stage kidney disease that requires hemodialysis, a treatment in which a machine filters waste from the blood. Hemodialysis is a precursor to kidney transplant. To prepare for it, patients...

by Bioengineer.org - The International Society for Stem Cell Research (ISSCR) has unveiled an innovative and comprehensive resource entitled Best Practices for the Development of Pluripotent Stem Cell-Derived Cellular Therapies, marking a pivotal advancement in the...

by Technology Networks - In a first-in-human Phase 1/2a clinical trial, adult stem cells improved vision in patients with macular degeneration. In the United States, age-related macular degeneration is a leading cause of irreversible vision loss in people who are 60...

By Drug Target Review - A USC Stem Cell-led research team have made a big breakthrough in their efforts to build mouse and human synthetic kidneys. In a new paper published in Cell Stem Cell, the scientists describe generating more mature and complex lab-grown...