NEWS and OPINIONS

New stem cell approach could repair stroke-damaged brains
by Drug Target Review - A new experimental stem cell therapy shows promise in repairing brain damage after ischemic strokes – potentially allowing for the development of future treatments that extend the recovery window. Strokes are a leading worldwide cause of death...

Youngest Cedars-Sinai Stem Cell Donor Helps Doctors Treat Dad’s Leukemia
By Cedars Sinai - In July, Nick Mondek, MD, drove his healthy 9-year-old son Stephen to Cedars-Sinai on an important mission: To donate stem cells that might cure Mondek’s deadly blood cancer. Stephen’s donation would give Mondek a brand-new immune system—and make...

New Targets Emerge for Aggressive Small Cell Lung Cancer
By Sabrina Serani, Matthew Oser, MD - Targeted Oncology - While there have been notable breakthroughs for the treatment of small cell lung cancer (SCLC) in recent years, there is still a relative dearth of targeted therapies for this aggressive subtype. Researchers...

Stem cell transplant for stroke leads to brain cell growth and functional recovery in mice
by Wayne Lewis - Keck school of Medicine USC - When someone has a stroke — a leading worldwide cause of death and disability — time is of the essence. Almost nine out of 10 cases are ischemic strokes, caused by restricted blood flow in the brain, and the current...

Parkinson’s is on the rise. Here’s one future treatment giving researchers hope
By NPR - Parkinson's Disease affects around a million people in the United States, and that number is on the rise, in part because our population is getting older. Dr. Claire Henchcliffe is the chair of neurology at the University of California, Irvine. She's one of...

Researchers Develop “Off-the-Shelf” CAR T-Cell Therapy
By Technology Networks - Peking University scientists have developed a groundbreaking cancer therapy that could make life-saving treatment accessible to any patient, anywhere. A team led by Professor Wei Wensheng from Peking University, collaborating with the PLA...

Researchers Create 3D-Printed Artificial Skin That Allows Blood Circulation
By Wired Magazine - Swedish researchers have developed two types of 3D bioprinting technology to artificially generate skin containing blood vessels. It could be a breakthrough in the quest to regenerate damaged skin. When treating severe burns and trauma, skin...

New AI Tool Pinpoints Genes, Drug Combos To Restore Health in Diseased Cells
By Ekaterina Pesheva - Harvard Medical School - New AI tool accurately identifies multiple drivers of disease in cells and predicts therapies that can restore cells to healthy function. In a move that could reshape drug discovery, researchers at Harvard Medical School...

Evaluating the long-term efficacy of umbilical cord-derived mesenchymal stem cell therapy in retinitis pigmentosa: findings from a 1-to-4-year follow-up
By Stem Cells Translational Medicine - Background The objective of this study was to assess the long-term effectiveness and safety of implanting mesenchymal stem cells derived from umbilical cord tissue (UC-MSC) in patients diagnosed with retinitis pigmentosa (RP)....

CAR T’s biggest hurdle: solving the toxicity problem
By Drug Target Review - CAR T therapies are saving lives, but toxicities such as CRS and ICANS remain a major barrier. What will it take to overcome them? Chimeric antigen receptor (CAR) T-cell therapy is changing lives for patients with hard-to-treat cancers. By...

Key genetic characteristics of compatibility when transplanting blood cell-producing stem cells identified
by University of Geneva - MedicalXpress - Transplanting hematopoietic stem cells from healthy individuals is one of the possible treatments for blood cancers. In Switzerland, it involves nearly 300 patients per year. However, nearly half of transplants fail, mainly...

Overview of the application of nanogels in wound healing
By Journal of Drug Delivery Science and Technology - Abstract Wound healing is the process of tissue regeneration, which, under normal conditions, is a very time-consuming process. It is also very susceptible to complications such as infection and chronic...