NEWS and OPINIONS
Fixing Sugar Metabolism Shows Promise Against Dementia
by Arkadi Mazin - Lifespan Research Institute - This may have effects on a significant component of Alzheimer's. Scientists have shown that aberrant metabolism of glycogen in neurons is linked to the accumulation of harmful tau protein. Caloric restriction, genetic...
Stem Cell Bank Targets Alzheimer’s Genetic Risk
By Technology Networks Genomics Research - New stem cell platform models Alzheimer's risk using cells from people with high and low genetic predisposition. Researchers at the UK Dementia Research Institute at Cardiff University have developed a new stem cell resource...
“Leukemia-on-a-Chip” Offers a New Tool for Screening CAR T-Cell Therapy
By Technology Networks - Chimeric antigen receptor (CAR) T cell therapy represents a breakthrough in cancer treatment. By harnessing the body’s immune system, CAR T therapy provides a powerful, personalized treatment option that can be particularly effective for...
Partial Match Parity: Increasing the Donor Pool for Hematopoietic Stem Cell Transplantation
By: Charlotte Schubert, Ph.D. - University of Miami Miller School of Medicine - Blood cancer patients who may have previously struggled to find a donor for transplantation now have more options. A new study shows that patients achieve good outcomes with an partial...
Releasing a molecular ‘brake’ may help immune cells better fight cancer
By Van Andel Institute - Grand Rapids, MI - Van Andel Institute scientists and collaborators have discovered a potential treatment target that may re-energize dysfunctional or “exhausted” immune cells in their fight against cancer. The target is an immune checkpoint...
Mice Regenerate Ear Tissue When Vitamin A Genetic Switch is Flipped
By Genetic Engineering and Biotechnology News - By flipping an evolutionarily disabled genetic switch involved in vitamin A metabolism, researchers headed by a team at the National Institute of Biological Sciences, Beijing, have enabled ear tissue regeneration in...
How the First Customized Gene Therapy Was Created in Six Months
by Molly Coddington - Technology Networks - CRISPR gene therapy is changing the future of rare genetic disorder treatments. In May, news broke that a 10-month-old baby, KJ Muldoon, was doing well after receiving 3 doses of the world’s first personalized CRISPR...
FDA blocks new clinical trials that ship cells from US to China
By Nick Paul Taylor - Fierce Biotech - The FDA has stopped new clinical trials that export American citizens’ living cells from the U.S. to “China and other hostile countries for genetic engineering and subsequent infusion” back into American patients. Officials said...
Japan is helping lead the way in regenerative medicine
By Alex (Guangyao) Xu - The Japan Times - In a quiet operating room on Kyoto University’s medical campus, a team of researchers slipped a syringe of lab-grown neurons into the brain of a living person. Leading the trial was Jun Takahashi, a neurosurgeon with the kind...
Organ-Chips May Help Unlock the Mystery of ALS
By Christina Elston - Cedars Sinai - Cedars-Sinai’s Lifelike Laboratory Model Is a New Way for Investigators to Study Motor Neurons That Die in Patients With the Neurodegenerative Illness Using stem cells from patients with ALS (amyotrophic lateral sclerosis),...
3 progressive MS patients see lower disability with CAR T-cell therapy
by Marisa Wexler - Multiple Sclerosis News Today - A CAR T-cell therapy from Iaso Biotherapeutics was tolerated well and led to marked improvements in disability for three people with progressive forms of multiple sclerosis (MS), according to early data from a Phase 1...
Germany calls for medicine to treat aging, not just disease
By Eleanor Garth - Longevity.Technology - Leopoldina issues policy paper urging integration of geroscience into national healthcare and research infrastructure. Germany’s National Academy of Sciences Leopoldina has published a detailed policy paper calling for a...