by Andrew Saintsing, PhD - Drug Discovery News - When the world ground to a halt in 2020, news outlets regularly featured stories about how COVID-19 wreaked havoc on patients’ lungs. In millions of cases, an initial cough developed into full-blown pneumonia, which...

By Technology Networks - A single treatment with, a CRISPR-Cas9-based gene editing therapy, is enough to replace the daily medication of patients with hereditary angioedema (HAE), a condition characterized by severe, painful and sudden onset of swelling, sometimes...

By Ani Vahradyan - UCLA Broad Stem Cell Research Center - Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a first-of-its-kind experimental therapy that has the potential to enhance heart repair...

By Smriti Mallapaty - Nature - Ever since the first blood-forming stem cells were successfully transplanted into people with blood cancers more than 50 years ago, researchers have wondered whether they developed cancer-causing mutations. A unique study1 on the...

by Pennsylvania State University - MedicalXpress - Immunotherapies that mobilize a patient's own immune system to fight cancer have become a treatment pillar. These therapies, including CAR T-cell therapy, have performed well in cancers like leukemias and lymphomas,...

By BMC - Military Medical Research - Severe tissue defects present formidable challenges to human health, persisting as major contributors to mortality rates. The complex pathological microenvironment, particularly the disrupted immune landscape within these defects,...

By Gina Kolata - New York Times - After 44 days, Kendric Cromer, 12, left the hospital. While his family feels fortunate that he was the first to receive a treatment, their difficult experiences hint at what others will be up against. Kendric Cromer, 12, left...

by Duke-NUS Medical School - MedicalXpress - An international team of neuroscientists, led by Duke-NUS Medical School, have uncovered a mechanism that controls the reactivation of neural stem cells, which are crucial for repairing and regenerating brain cells. The...

by Wellcome Trust Sanger Institute - MedicalXpress - For the first time, researchers have created a single cell atlas of prenatal human skin to understand how skin forms, and what goes wrong in disease. Researchers from the Wellcome Sanger Institute, Newcastle...

By - Nature - Despite treatment advances, multiple myeloma (MM) remains incurable1. High-dose chemotherapy followed by autologous stem cell transplantation (ASCT) is considered the standard treatment for eligible patients2,3. Moreover, ASCT is reportedly effective and...

By A Donlan - Fred Hutch Cancer Center - During the COVID-19 pandemic, it quickly became clear that certain populations were particularly at risk for severe disease. Individuals undergoing hematopoietic cell transplants (HCT) or chimeric antigen receptor T-cell (CART)...

By Danielle H. Cho - Daily Bruin - UCLA researchers have found a gene that may have implications for treating blood-related genetic diseases and cancers. All types of blood cells come from blood stem cells, said Júlia Aguadé-Gorgorió, the first author of the paper...