NEWS and OPINIONS

Xenogeneic-free culture of human intestinal stem cells for scalable, clinical-grade stem cell therapy
By Nature Communications - The need for basement membrane extract (BME) with undefined constituents, such as Matrigel, for intestinal stem cell (ISC) culture in traditional systems poses a significant barrier that must be overcome for the development of...

The global divide between longer life and good health
By Susan Buckles - Mayo Clinic - Rochester, Minn. — People around the globe are living longer — but not necessarily healthier — lives, according to Mayo Clinic research. A study of 183 World Health Organization (WHO) member countries found those additional years of...

Tiny sensors offer new hope for faster bone injury recovery
by Rachel Lukowicz-Bedford, University of Oregon - MedicalXpress - Tiny implantable sensors are helping University of Oregon researchers optimize the process of recovery from severe bone injuries. Scientists at the UO's Phil and Penny Knight Campus for Accelerating...

Using cellular therapy to treat cancer, and beyond
By Scott Reading - University of Michigan Medicine - A cell therapy clinician talks about the treatment and its promising future to treat other diseases, too Advancements in using a person’s own cells to treat disease have been growing for years. These include...

Keto diet metabolite may power up CAR T cells to kill cancer
By Penn Today - Laboratory studies reveal a potentially low-tech intervention to improve personalized cell therapy. A simple dietary supplement may provide a new approach to boost CAR T cell function, according to a study from researchers in Penn’s Perelman School of...

Scientists Decipher How Marine Worms Regrow Lost Body Parts
by Technology Networks - Marine worms regenerate lost body parts by dedifferentiating cells, offering insights into natural cell reprogramming. Researchers at the Max Perutz Labs have uncovered how marine worms regenerate lost body segments. The study reveals that...

What can we learn from 2024’s biotech IPOs?
By Ayla Ellison, James Waldron - Fierce Biotech - After a promising start to the year, the biotech IPO market picked up steam again late this summer, with notable offerings from companies like Upstream, Septerna and BioAge. But what does this mean for the sector? Is...

High-fiber diet cuts risk of rejected bone marrow and stem cell transplants, cancer research discovers
By Benjamin Ferrer - Nutrition Insight - Scientists and physicians with the US-based cancer research and treatment organization City of Hope are presenting new research on high-fiber dietary interventions for bone marrow and stem cell transplant patients at risk for...

How FIRM is Shaping Regenerative Medicine in Japan
by Bernice Lottering - Gene Online - Regenerative medicine, as a whole, is in a critical position to transform healthcare and confront several critical challenges that threaten its widespread adoption. High costs, complex development processes, and intricate...

Is exosome therapy the future of hair loss treatment? Expert insights
by Dr Rinky Kapoor - Healthcare Radius - Exosomes, which are nanoscale extracellular vesicles derived from mesenchymal stem cells (MSCs), encapsulate a diverse array of bioactive molecules, including proteins, lipids, and nucleic acids, that facilitate intercellular...

Ketogenic Diet Enhances CAR-T Cancer Therapy
By Neuroscience News - Researchers have found that a ketogenic diet boosts CAR T cell therapy effectiveness by enhancing tumor control and survival in mice with lymphoma. The key is beta-hydroxybutyrate (BHB), a metabolite produced during ketosis, which CAR T cells...

Socioeconomic Barriers Limit Access to Lifesaving Stem Cell Transplants in AML
By Silas Inman - Cancer Network News - The ability to undergo an allogeneic hematopoietic stem cell transplant (allo-HCT), the only potentially curative therapy for patients with acute myeloid leukemia (AML), is significantly influenced by socioeconomic factors with...