Behind the FDA’s Elimination of REMS Program for CAR T-Cell Therapies

by admin | Nov 25, 2025 | Bernie Siegel’s WORLD STEM CELL SUMMIT BLOG, News and Opinions

By Jonah Feldman, Frederick Locke, MD – Targeted Oncology – On June 26, 2025, the FDA announced the elimination of the Risk Evaluation and Mitigation Strategy (REMS) program that applied to 6 chimeric antigen receptor (CAR) T-cell therapies approved to...

Scientists discover how hair cells can help heal skin faster

by admin | Nov 24, 2025 | Bernie Siegel’s WORLD STEM CELL SUMMIT BLOG, News and Opinions

By Rockefeller University – ScienceDaily Scientists found that low serine levels spark a shift in hair stem cells, transforming them into wound-healing experts — with diet playing a possible role. Rockefeller scientists uncovered how hair follicle stem cells can...

Engineered Bone Marrow Model Advances CRISPR-CAR T Research in AML

by admin | Nov 21, 2025 | Bernie Siegel’s WORLD STEM CELL SUMMIT BLOG, News and Opinions

By Genetic Engineering and Biotechnology News – Scientists at the University of Glasgow developed a bioengineered bone marrow (BM) model that helped them to evaluate potential use of a combined CRISPR-CAR T cell therapy in the treatment of acute myeloid...

Stem Cells Prevent Heart Failure After Heart Attack

by admin | Nov 20, 2025 | Bernie Siegel’s WORLD STEM CELL SUMMIT BLOG, News and Opinions

By American Medical Journal – A NEW phase 3 clinical trial has revealed that stem cells can help prevent heart failure in patients recovering from acute myocardial infarction. The study found that intracoronary infusion of mesenchymal stem cells significantly...

We need to start thinking of AI as “normal”

by admin | Nov 19, 2025 | Bernie Siegel’s WORLD STEM CELL SUMMIT BLOG, News and Opinions

By James O’Donnell – MIT Technology Review – As technologists frame AI as either utopian or dystopian, two researchers offer a third option. Right now, despite its ubiquity, AI is seen as anything but a normal technology. There is talk of AI systems...

Anti-fibrotic effect of human amniotic fluid stem cells in biliary epithelial-mesenchymal transition of liver ductal organoid

by admin | Nov 18, 2025 | Bernie Siegel’s WORLD STEM CELL SUMMIT BLOG, News and Opinions

By Stem Cells Translational Medicine – Abstract Purpose In biliary atresia (BA), it has been demonstrated that biliary epithelial-mesenchymal transition (EMT) of reactive ductular cells is associated with liver fibrosis. This study aimed to develop an ex vivo...