New Tool Identifies Proteins That Control Gene Activity

by admin | Oct 21, 2025 | Bernie Siegel’s WORLD STEM CELL SUMMIT BLOG, News and Opinions

by Weill Cornell Medicine – he SCOPE system can capture proteins binding to regions of DNA that control gene expression. The illustration depicts part of the process where a small guide RNA delivers a protein bearing a special amino acid to the desired region....

Takeda Exits Cell Therapy Amid Strategic Pivot, Dealing Blow to Once Promising Modality

by admin | Oct 20, 2025 | Bernie Siegel’s WORLD STEM CELL SUMMIT BLOG, News and Opinions

by Tristan Manalac – BioSpace – Takeda is looking to offload its cell therapy platform and preclinical assets to a yet-unidentified external partner. 137 employees will be let go as part of the move. Takeda will no longer invest in cell therapies moving...

New CAR T therapy targets solid tumours safely and effectively

by admin | Oct 17, 2025 | Bernie Siegel’s WORLD STEM CELL SUMMIT BLOG, News and Opinions

By Drug Target Review – USC researchers have engineered CAR T cells to deliver a dual protein therapy that targets solid tumours – offering hope for cancers previously resistant to treatment. Chimeric antigen receptor (CAR) T-cell therapy, which uses a patient’s...

High-throughput 3D engineered paediatric tumour models for precision medicine

by admin | Oct 16, 2025 | Bernie Siegel’s WORLD STEM CELL SUMMIT BLOG, News and Opinions

By Molecular Systems Biology – Abstract Precision medicine for paediatric and adult cancers that incorporates drug sensitivity profiling can identify effective therapies for individual patients. However, obtaining adequate biopsy samples for high-throughput...

This medical startup uses LLMs to run appointments and make diagnoses

by admin | Oct 15, 2025 | Bernie Siegel’s WORLD STEM CELL SUMMIT BLOG, News and Opinions

By Grace Huckins – MIT Technology Review – Imagine this: You’ve been feeling unwell, so you call up your doctor’s office to make an appointment. To your surprise, they schedule you in for the next day. At the appointment, you aren’t rushed through...

Distal lung organoids derived from adult stem cells as novel tools in deciphering mechanisms of lung regeneration, infection, and cancer

by admin | Oct 14, 2025 | Bernie Siegel’s WORLD STEM CELL SUMMIT BLOG, News and Opinions

By Stem Cells Translational Medicine – Introduction While lung research has made great strides in understanding lung physiology, lung pathology still presents a major burden to patients and healthcare systems globally. To develop new effective therapeutics to...