A Review of Human Disease Models in Drug Development

A Review of Human Disease Models in Drug Development

by admin | Sep 5, 2023 | Bernie Siegel’s WORLD STEM CELL SUMMIT BLOG, News and Opinions

By Florina Gobel – Center for Contemporary Sciences In the article Human disease models in drug development published in Nature, the authors delve into the critical role of human disease models in drug development, emphasizing the importance of bridging the gap...

Modified neural stem cells for spinal cord injury

by admin | Sep 1, 2023 | Bernie Siegel’s WORLD STEM CELL SUMMIT BLOG, News and Opinions

By Drug Target Review Using genetically modified human neural stem cells (hNSCs), researchers demonstrated that targeted manipulation of a specific gene expression within hNSCs can facilitate the restoration of damaged neural circuits and recovery of locomotor...

Wiping stem cells ‘clean’ could make them easier to produce

by admin | Aug 31, 2023 | Bernie Siegel’s WORLD STEM CELL SUMMIT BLOG, News and Opinions

By Jason Arunn Murugesu – NewScientist A technique for reprogramming adult cells that removes any trace of their origins could help produce stem cells at larger scales A new way to turn adult human cells into ultra-flexible stem cells could make it easier to...

Building muscle in the lab

by admin | Aug 30, 2023 | Bernie Siegel’s WORLD STEM CELL SUMMIT BLOG, News and Opinions

by Fabio Bergamin – ETH Zurich Professor Ori Bar-Nur and his team grow muscle cells in the laboratory. In this case, they are mouse cells, but the researchers are also interested in human and cow cells. Promising applications resonate with both: human muscle...

How mRNA Could Safely Replace Blood Stem Cell Transplantation

by admin | Aug 29, 2023 | Bernie Siegel’s WORLD STEM CELL SUMMIT BLOG, News and Opinions

by William A. Haseltine – Forbes At present, the only way to cure genetic blood disorders such as sickle cell anemia and thalassemia is to reset the immune system with a stem cell transplantation. Only a fraction of patients elects this procedure, as the process...

Polyploid cells, which have extra copies of their genomes, may help tissues respond to injuries and species survive cataclysms

by admin | Aug 28, 2023 | Bernie Siegel’s WORLD STEM CELL SUMMIT BLOG, News and Opinions

By Elizabeth Pennisi – Science When Vicki Losick got her Ph.D. and joined a fruit fly lab at the Carnegie Institution for Science in 2008, its head announced that he expected his postdocs to launch new fields of inquiry. She chose a then-fashionable focus: stem...