By Karen Guzman – Yale News –
Yale scientists have engineered natural killer cells that eliminate solid tumors in mouse models. The study may lead to a simpler, “off the shelf” immunotherapy for hard-to-treat cancers.
Since scientists first discovered that human immune cells could be modified to become cancer-fighting agents, they’ve been trying to engineer a cell that’s effective against solid tumors, which account for the vast majority of cancer cases.
In a key advance in meeting this “holy grail challenge” in the field of cancer cell therapy, a team of Yale scientists led by geneticist Sidi Chen has revealed how immune cells can be “boosted” to target and eradicate solid tumors.
