By Esra Öz – NewScientist –
Immune cells are most commonly engineered to kill cancers, but now, scientists have shown the technique makes the gut lining of older mice resemble that of younger mice, raising hopes that the same approach could work in people
As we age, the cells that line our intestine gradually lose their ability to renew themselves, which is important for maintaining good immune health. But now, scientists have reversed this process in older mice using genetically engineered immune cells.
Known as CAR T-cell therapy, this is most commonly used to treat some kinds of blood cancer. This involves collecting a sample of someone’s immune cells, called T-cells, reprogramming them in the laboratory to target and kill cancer cells, multiplying them, and then infusing them back into the bloodstream.
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