by Alejandra Manjarrez, PhD – Exploring Drug Discovery and Development =
Macrophage-based therapies for liver cirrhosis are entering clinical trials, but key challenges remain before they become a viable treatment.
Macrophages — key players of the immune system — swiftly engulf harmful cells and debris, their lesser-known talent lies in healing: they ease inflammation, break down scar tissue, and trigger organ repair.
For over a decade, scientists have explored whether these regenerative powers could be harnessed to treat one of the most challenging liver conditions: cirrhosis. This chronic disease, marked by irreversible scarring, severely limits liver function, and remains notoriously hard to manage.
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