By University of Geneva –
Acute myeloid leukaemia is one of the deadliest cancers. Leukaemic stem cells responsible for the disease are highly resistant to treatment. A team from the University of Geneva (UNIGE), University Hospital of Geneva (HUG), and Inserm has made a breakthrough by identifying some of the genetic and energetic characteristics of these stem cells, notably a specific iron utilisation process. This process could be blocked, leading to the death or weakening of these stem cells without affecting healthy cells. These results, published in Science Translational Medicine, pave the way for new therapeutic strategies.
