By Drug Target Review –
Researchers found that genetic depletion of cyclophilin A results in stem cells distinctively lacking intrinsically disordered proteins.
Scientists at Baylor College of Medicine have discovered the enzyme cyclophilin A is crucial for hematopoietic stem cells (HSCs) to retain their regenerative potential and avert the effects of aging.
Although HSCs normally remain dormant within bone marrow, they can activate and replenish blood cells continuously, maintaining a fairly youthful profile throughout the life of an organism.
