Researchers at the Francis Crick Institute and UCL Queen Square Institute of Neurology, working with technology company Faculty AI, have shown that machine learning can accurately predict subtypes of Parkinson’s disease using images of patient-derived stem cells.
Their work, published today in Nature Machine Intelligence, has shown that computer models can accurately classify four subtypes of Parkinson’s disease, with one reaching an accuracy of 95%. This could pave the way for personalised medicine and targeted drug discovery.
Parkinson’s disease is a neurodegenerative condition impacting movement and cognition. Symptoms and disease progression vary from person to person due to differences in the underlying mechanisms causing the disease.
