A world-first trial is investigating if stem cell transplantation could be used in patients with aggressive multiple sclerosis (MS) as a first-line treatment.
The study launched by the University of Sheffield and Sheffield Teaching Hospitals NHS Foundation Trust will trial the pioneering therapy in patients with highly active MS which is not responding to drug treatment or as a first-line treatment for patients with the aggressive form of the inflammatory and neurodegenerative disease.
The £2.3m StarMS study, which has already opened its doors to patients in Sheffield, is now being launched in multiple sites across the UK. It will be the first to compare how effectively autologous hematopoietic stem cell transplantation (AHSCT) is when compared with four other highly effective drug treatments which have shown great promise in clinical trials (alemtuzumab, ocrelizumab, ofatumumab and cladribine).
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