Cancer breakthrough uses CRISPR to target extra chromosomes

Jul 12, 2023

By Michael Irving – New Atlas

Yale scientists have discovered a new potential treatment avenue to fight cancer. Using CRISPR gene-editing, the team eliminated extra chromosomes from cancer cells and found that they could no longer grow out of control.

Healthy human cells have 23 pairs of chromosomes, but it’s been observed for over a century that the majority of cancer cells have extras. This condition is known as aneuploidy, but its exact role in cancer remained a mystery – was it a root cause of cancer or just a symptom of it? In a new study, scientists at Yale investigated that role.

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