Web portal marks new phase in the iPSC Neurodegenerative Disease Initiative
by Lindsey Shapiro, PhD – ALS News Today
A number of stem cell lines developed to better understand how certain genetic factors might contribute to amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases is now available to scientists worldwide.
The cell lines were engineered by researchers at the National Institutes of Health Center for Alzheimer’s and Related Dementias (NIH CARD) to carry mutations associated with specific neurodegenerative diseases.
Stem cell lines currently available contain mutations linked to ALS, frontotemporal dementia, Alzheimer’s disease and Parkinson’s disease. They now can be ordered through a web portal run by the Jackson Laboratory.
The launch of the portal marks a new phase in the iPSC Neurodegenerative Disease Initiative (iNDI), a project launched in 2021 to promote stem-cell based neurodegenerative disease research. iNDI is a collaborative effort between NIH CARD, Jackson Laboratory, and the Chan Zuckerberg Initiative.